The Desert Rangelands sub-region covers largely the inner east area of WA and incorporates the IBRA bioregions of the Great Sandy Desert, the Gibson Desert, the Little Sandy Desert and the Great Victoria Desert.
The sub-region is sparsely populated, the main population consisting of Indigenous Australian communities and mining centers. The Aboriginal people of the desert that Rangelands have engaged with include those of the Native Title claim and determined areas of Martu, Birriliburu, Ngururrpa, Yilka, Spinifex and Pilki.
Due to its expanse, the Desert Rangelands sub-regions is diverse in its landforms and climate.
To the north, the Great Sandy Desert contains large Ergs, often consisting of longitudinal dunes, with the Wolfe Creek meteorite impact crater located in the northeast. The vegetation is dominated by spinifex and animals include feral camels, dingos, goannas and numerous species of lizard and birds.
To the east of the Great Northern Highway south of Newman and approximately 200 kilometres north of Wiluna is the Little Sandy Desert. It's landforms, fauna and flora, etc., are all similar to the Great Sandy Desert. Both deserts are crossed by the Canning Stock Route.
Centrally, between the salt lakes of Lake Disappointment and Lake Macdonald along the Tropic of Capricorn is the Gibson Desert, large portions of which are characterised by gravel-covered terrains covered in thin desert grasses. The undulating red sand plains and dunefields are rich in iron.
To the sourth, lies The Great Victoria, the largest desert in Australia, consisting of many small sandhills, grassland plains, areas with a closely packed surface of pebbles and salt lakes.